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OpenClinical trial: Not allowed

Limited Competition: Specific Pathogen Free Macaque Colonies to Support HIV/AIDS Research (U42 Clinical Trial Not Allowed)

National Institutes of Health (NIH) · NIH Institute/Center · PAR-24-129

Source: Grants.gov · View original posting ↗

Award
Amount not listed
Deadline
Sep 25, 2026
Letter of intent
Mechanism
Duration
Expected awards
Funding cycle
Standard NIH dates
Open date
Jan 22, 2024
Total funding
Clinical trial
Not allowed
Higher educationGovernmentForeign entities

Description

The purpose of this Notice of Funding Opportunity (NOFO) is to provide continuing support for specific pathogen-free (SPF) macaque colonies previously funded under the auspices of PAR-21-089 and PAR-18-669 that support Human Immunodeficiency Virus (HIV)/Acquired Immunodeficiency Syndrome (AIDS) research. Breeding colonies are essential to sustain appropriate SPF macaques for research related to HIV/AIDS. Pedigree SPF macaques are free of certain viruses, which may confound the results of HIV/AIDS-related investigations or present a risk to the personnel who care for the animals. The SPF macaques are genetically characterized for major histocompatibility complex (MHC) class I types, because MHC class I genotypes have large effects on macaque immune responses to Simian Immunodeficiency Virus (SIV) that can induce AIDS in nonhuman primates (NHPs) and on human immune responses to HIV.

Data notes: award amount not published in the source feed; administering NIH institute could not be identified from the opportunity number.