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OpenR33Clinical trial: Required

Early Stage Testing of Pharmacologic or Neuromodulatory Device-based Interventions for the Treatment of Mental Disorders (R33- Clinical Trial Required)

National Institutes of Health (NIH) · NIH Institute/Center · PAR-25-183

Source: Grants.gov · View original posting ↗

Award
Amount not listed
Deadline
Oct 15, 2027
Letter of intent
Mechanism
R33
Duration
Expected awards
Funding cycle
Standard NIH dates
Open date
Nov 26, 2024
Total funding
Clinical trial
Required
GovernmentHigher educationNonprofitSmall businessForeign entities

Research areas

Basic mechanisms & biologyTherapeutics & drug discoveryClinical trials

Auto-classified from the title and description (keyword-based) — may be imperfect.

Description

NIMH requires an experimental therapeutics approach for the development and testing of therapeutic interventions, in which studies both evaluate the clinical effect of an intervention and generate information about the mechanisms underlying a disorder or an intervention response. As part of NIMHs Clinical Trial Pipeline, this NOFO encourages early stage testing of pharmacologic interventions with novel mechanisms of actions or device-based interventions. More specifically, this NOFO is intended to support early stage testing of pharmacologic or device-based interventions using a protocol design where the presumed mechanism of action of the intervention is adequately tested, to provide meaningful information where target modulation yields a dose-dependent neurophysiological/clinical/behavioral effect.

Data notes: award amount not published in the source feed; administering NIH institute could not be identified from the opportunity number.