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OpenR01Clinical trial: Optional / allowed

Innovative Screening Approaches and Therapies for Screenable Disorders in Newborns (R01 - Clinical Trial Optional)

National Institutes of Health (NIH) · NIH Institute/Center · PAR-25-265

Source: Grants.gov · View original posting ↗

Award
Amount not listed
Deadline
Nov 16, 2027
Letter of intent
Mechanism
R01
Duration
Expected awards
Funding cycle
Standard NIH dates
Open date
Dec 2, 2024
Total funding
Clinical trial
Optional / allowed
Established investigatorHigher educationSmall businessGovernmentNonprofitForeign entities

Funding context

16%of applications funded

Based on FY2024 NIH (all institutes) R01 applications (5,385 of 33,139 applications awarded).

Institute-specific data wasn’t available — showing the NIH-wide rate for this mechanism.

Payline: NIH discontinued percentile paylines for 2026 under its Unified Funding Strategy ↗ — scores are now weighed in context rather than against a fixed cutoff.

NIH-wide R01, all institutes.

Aggregate historical data by institute, mechanism, and fiscal year — context for planning, not a prediction for this opportunity. Source ↗

Research areas

Biomarkers & diagnosticsTherapeutics & drug discovery

Auto-classified from the title and description (keyword-based) — may be imperfect.

Description

This FOA encourages research relevant to the development of novel screening approaches and/or therapeutic interventions for potentially fatal or disabling conditions that have been identified through newborn screening, as well as for "high priority" genetic conditions where screening may be possible in the near future.Having an accurate screening test, as well as demonstrating the benefits of early intervention or treatment, are important criteria for including a condition on a newborn screening panel. This FOA defines a "high priority" condition as one where screening is not currently recommended, but infants with the condition would significantly benefit from early identification and treatment.

Data notes: award amount not published in the source feed; administering NIH institute could not be identified from the opportunity number.