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OpenR01Clinical trial: Optional / allowed

Advancing Bioinformatics, Translational Bioinformatics and Computational Biology Research (R01 Clinical Trial Optional)

National Institutes of Health (NIH) · NIH Institute/Center · PAR-26-040

Source: Grants.gov · View original posting ↗

Award
Up to $250K
Deadline
Mar 5, 2029
Letter of intent
Mechanism
R01
Duration
Expected awards
10
Funding cycle
Standard NIH dates
Open date
Feb 11, 2026
Total funding
$2.5M total
Clinical trial
Optional / allowed
Established investigatorHigher educationNonprofitGovernmentSmall businessForeign entities

Funding context

16%of applications funded

Based on FY2024 NIH (all institutes) R01 applications (5,385 of 33,139 applications awarded).

Institute-specific data wasn’t available — showing the NIH-wide rate for this mechanism.

Payline: NIH discontinued percentile paylines for 2026 under its Unified Funding Strategy ↗ — scores are now weighed in context rather than against a fixed cutoff.

NIH-wide R01, all institutes.

Aggregate historical data by institute, mechanism, and fiscal year — context for planning, not a prediction for this opportunity. Source ↗

Research areas

Basic mechanisms & biologyData & infrastructure

Auto-classified from the title and description (keyword-based) — may be imperfect.

Description

The National Library of Medicine (NLM) seeks applications for research projects that drive groundbreaking innovation and advanced development in the fields of bioinformatics, translational bioinformatics, and computational biology. The primary goal of this initiative is to support the creation and implementation of cutting-edge methods, tools, and approaches that can transform the landscape of biomedical data science. This NOFO aims to address the growing need to leverage transformative technologies — such as artificial intelligence (AI), machine learning, and large-scale computational platforms — to extract actionable knowledge from vast, diverse, and complex biological datasets. By enabling more effective interpretation and integration of multi-dimensional biological and biomedical data, this research will ultimately contribute to improving individual and population health outcomes.

Data notes: administering NIH institute could not be identified from the opportunity number.